Toxicology Rock Star: The Inspiring Story of Dr. Edward Calabrese, Hormesis and the Dose Response
Huffington Post Blog - August 2013
by Amy Rothenberg, ND
In last week's issue of Critical Review of Toxicology, Edward Calabrese, Ph.D., lays out his understanding of the mechanisms at play in hormesis.* Hormesis is a dose-response phenomenon characterized by low-dose stimulation and high-dose inhibition. Historically, dose-responses have been thought to occur in a linear fashion from low-dose to high. A non-linear response, such as the hormetic response, has potential application in most every scientific field. This paper offers the first wide-reaching documentation of mechanisms of hormetic dose/concentration responses. For the past 20 years, Calabrese has been at the center of much of the research on hormesis.